Side Effects and Safety: CBD Vs THC
The psychoactive properties of THC can cause temporary side effects: Memory impairments
Lowered reaction time
Increased heart rateCoordination problems
While there is a risk of some negative side effects from THC, according to the National Cancer Institute it is not possible to have a fatal overdose. Some studies have found evidence that cannabis strains high in THC can cause long-term negative psychiatric effects when consumed by adolescents, including increasing the risk of psychiatric disorders like schizophrenia.
Research indicates even large doses of CBD are well tolerated and safe. There have been some reports of dry mouth, light-headedness, and drowsiness. A recent research review examining the safety and side effects of CBD concluded that CBD appeared to be safe in humans and animals. Even chronic use of CBD by humans showed to cause no adverse neurological, psychiatric, or clinical effects.
CBD and THC Drug Interactions
Virtually all chemical compounds, from over-the-counter drugs and prescription pharmaceuticals to illicit substances, interact with other compounds. There are, for example, 82 identified drug interactions
with caffeine (of which 25 are classified as moderately severe to severe). Even seemingly benign substances, like grapefruit, are known to interact with many prescription drugs. When it comes to cannabis, most potential interactions that have been identified are relatively mild. And, in fact, some drugs seem to work together with cannabis favourably.
* But, before we dive deep on some of the most common drugs people combine with cannabis, it’s important to understand the difference between an “additive” and “synergistic” effect. Additive simply means the interaction between two chemicals equals the sum of their parts (e.g. 1+1 = 2). Synergistic means that when two chemicals interact, the effect is greater than the sum of their parts (e.g. 1+1 = 3. Sounds like “alternative math!”). Likewise, keep in mind that THC /CBD ratios and different strain profiles (with variable cannabinoid and terpene profiles) can influence effects.
Note: in some cases, cannabis may actually increase the effectiveness or potency of other drugs. But, even if the interaction is potentially beneficial, close monitoring by a medical professional, along with regular blood work, is important as a patient may need adjust their dosing accordingly.
Dr. Pierre Milot, PhD., PhD. (tc)
Life Transitions / Grief Recovery Counsellor
CBD-Rich Hemp Sales Consultant
Redmond House, Winchester ON.